3033060-68-0
3033060-68-0
Chemical Structure
LSD1-IN-16
- CAS No.: 3033060-68-0
- Formula:C20H18N2OS
- Molecular Weight:334.43
IUPAC Name: N-(3-chloro-2-((5-((2,6-difluoro-3,5-dimethoxybenzyl)oxy)-4,6-dimethylpyrimidin-2-yl)amino)-5-fluorophenyl)acrylamide
InChIKey: ZSVGAQYLNBWEPX-UHFFFAOYSA-N
SMILES: NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CC=CS4)=C3)=O
Biological Activity: LSD1-IN-16 (compound 4b) is a potent LSD1 inhibitor. LSD1-IN-16 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.015, 0.024, and 0.366 μM, respectively. LSD1-IN-16 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 15.2 μM[1].
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LSD1-IN-16 | LSD1-IN-16 (compound 4b) is a potent LSD1 inhibitor. LSD1-IN-16 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.015, 0.024, and 0.366 μM, respectively. LSD1-IN-16 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 15.2 μM. | |||||||||||||||||||||
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Keywords
