3033235-80-9
3033235-80-9
Chemical Structure
Akt/NF-κB/JNK-IN-1
- CAS No.: 3033235-80-9
- Formula:C22H22N2O6
- Molecular Weight:410.42
IUPAC Name: N-(2-(8-hydroxy-3-methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)ethyl)benzamide
InChIKey: OAPGKZKRIKMMPB-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CC(OCC2=CC3=C(C(O)=C2)C(C4=C(C=CC=C4C3=O)O)=O)=O
Biological Activity: Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signaling pathways. Akt/NF-κB/JNK-IN-1 inhibits nitric oxide production with an IC50 of 3.15 μM. Akt/NF-κB/JNK-IN-1 shows anti-inflammatory activities[1].
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Akt/NF-κB/JNK-IN-1 | Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signaling pathways. Akt/NF-κB/JNK-IN-1 inhibits nitric oxide production with an IC50 of 3.15 μM. Akt/NF-κB/JNK-IN-1 shows anti-inflammatory activities. | |||||||||||||||||||||
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References
Keywords
