3033425-97-4
3033425-97-4
Chemical Structure
HIV-1 inhibitor-41
- CAS No.: 3033425-97-4
- Formula:C16H15F2N3OS
- Molecular Weight:335.37
IUPAC Name: 2-methyl-1-(p-tolyl)propan-1-amine hydrochloride
InChIKey: HYGDGECYHFFCPW-UHFFFAOYSA-N
SMILES: CC1=C(N=C(NC1=O)SC(C)C)C(C2=C(C=CC=C2F)F)C#N
Biological Activity: HIV-1 inhibitor-41 (Compound B23) is an orally active non-nucleoside HIV-1 reverse transcriptase inhibitor with EC50 values of 20.8 nM and 50 nM against HIV-1 WT and mutant E138K strain, respectively. HIV-1 inhibitor-41 shows low hERG, no apparent CYP enzymatic inhibition and no acute toxicity[1].
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HIV-1 inhibitor-41 | HIV-1 inhibitor-41 (Compound B23) is an orally active non-nucleoside HIV-1 reverse transcriptase inhibitor with EC50 values of 20.8 nM and 50 nM against HIV-1 WT and mutant E138K strain, respectively. HIV-1 inhibitor-41 shows low hERG, no apparent CYP enzymatic inhibition and no acute toxicity. | |||||||||||||||||||||
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References
Keywords
