3034838-06-4
3034838-06-4
Chemical Structure
EGFR-PK/JNK-2-IN-1
- CAS No.: 3034838-06-4
- Formula:C22H17ClN4O3S
- Molecular Weight:452.91
InChIKey: KWQRLHRLFZGQKL-UHFFFAOYSA-N
SMILES: ClC(C=C1)=CC=C1C2=CC(C(NC3=CC=C(S(=O)(N)=O)C=C3)=O)=NN2C4=CC=CC=C4
Biological Activity: EGFR-PK/JNK-2-IN-1 (Compound 6c) is a dual inhibitor of EGFR-PK and JNK-2 with IC50s of 2.7 and 3.0 μM, respectively. EGFR-PK/JNK-2-IN-1 can induce apoptosis and induce cell cycle arrest at different cell phases. EGFR-PK/JNK-2-IN-1 can be used for the research of cancer[1].
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EGFR-PK/JNK-2-IN-1 | EGFR-PK/JNK-2-IN-1 (Compound 6c) is a dual inhibitor of EGFR-PK and JNK-2 with IC50s of 2.7 and 3.0 μM, respectively. EGFR-PK/JNK-2-IN-1 can induce apoptosis and induce cell cycle arrest at different cell phases. EGFR-PK/JNK-2-IN-1 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
