3040024-62-9
3040024-62-9
Chemical Structure
NLRP3-IN-42
- CAS No.: 3040024-62-9
- Formula:C29H27F3N2O3S2
- Molecular Weight:572.66
InChIKey: SOCCSZXWSGDUBN-UHFFFAOYSA-N
SMILES: CCCNS(=O)(C1=CC=C(C2=CC=CC=C2N(CC3=CC=C(C(F)(F)F)C=C3)C(CC4=CSC=C4)=O)C=C1)=O
Biological Activity: NLRP3-IN-42 (compound H28) is a potent NLRP3 inhibitor with an KD value of 1.15 µM. NLRP3-IN-42 decreases the LPS (HY-D1056) induced protein expression of cleaved-caspase-1 (p20). NLRP3-IN-42 selectively inhibits IL-1β release[1].
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NLRP3-IN-42 | NLRP3-IN-42 (compound H28) is a potent NLRP3 inhibitor with an KD value of 1.15 µM. NLRP3-IN-42 decreases the LPS (HY-D1056) induced protein expression of cleaved-caspase-1 (p20). NLRP3-IN-42 selectively inhibits IL-1β release. | |||||||||||||||||||||
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References
Keywords
