3046142-30-4
Chemical Structure
Anti-osteoporosis agent-4
- CAS No.: 3046142-30-4
- Formula:C26H26ClN3O7S
- Molecular Weight:560.02
InChIKey: HBLBCOGDJWFKPM-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(NC(COC3=CC=CC=C3Cl)=O)C(N4CCOCC4)=C2)=O
Biological Activity: Anti-osteoporosis agent-4 (Compound 11h) inhibits differentiation of primary osteoclasts. Anti-osteoporosis agent-4 attenuates RANKL-induced osteoclastogenesis. Anti-osteoporosis agent-4 inhibits osteoclast formation with an IC50 value of 358.29 nM. Anti-osteoporosis agent-4 inhibits PI3K/AKT and IκBα/NF-κB signaling pathway activation[1].
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Anti-osteoporosis agent-4 | Anti-osteoporosis agent-4 (Compound 11h) inhibits differentiation of primary osteoclasts. Anti-osteoporosis agent-4 attenuates RANKL-induced osteoclastogenesis. Anti-osteoporosis agent-4 inhibits osteoclast formation with an IC50 value of 358.29 nM. Anti-osteoporosis agent-4 inhibits PI3K/AKT and IκBα/NF-κB signaling pathway activation. | |||||||||||||||||||||
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Keywords