3046390-54-6
Chemical Structure
TRPV4-IN-5
- CAS No.: 3046390-54-6
- Formula:C20H22Cl3N3O3S
- Molecular Weight:490.83
InChIKey: CHBBCFXORPTZLQ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(S(=O)(N2CCN(C(C)C)CC2)=O)C=C1)C3=C(Cl)C=C(Cl)C=C3Cl
Biological Activity: TRPV4-IN-5 (Compound 1f) is a potent TRPV4 inhibitor (IC50 = 0.46 μM). TRPV4-IN-5 significantly alleviates the symptoms of acute lung injury induced by lipopolysaccharide (HY-D1056) in mice[1].
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TRPV4-IN-5 | 98.77% | TRPV4-IN-5 (Compound 1f) is a potent TRPV4 inhibitor (IC50 = 0.46 μM). TRPV4-IN-5 significantly alleviates the symptoms of acute lung injury induced by lipopolysaccharide (HY-D1056) in mice. | ||||||||||||||||||||
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Keywords