3049205-78-6
3049205-78-6
Chemical Structure
Anti-MRSA agent 7
- CAS No.: 3049205-78-6
- Formula:C22H20BrF2N3O4
- Molecular Weight:508.31
IUPAC Name: 4-bromo-3,5-difluoro-N-((3S,6R)-6-(((6-methoxy-1,5-naphthyridin-4-yl)oxy)methyl)tetrahydro-2H-pyran-3-yl)benzamide
InChIKey: NHXTWWVJRWMAAW-UONOGXRCSA-N
SMILES: COC1=NC2=C(N=CC=C2OC[C@H]3CC[C@@H](CO3)NC(C4=CC(F)=C(C(F)=C4)Br)=O)C=C1
Biological Activity: Anti-MRSA agent 7 (Compound 12) is a potent antibacterial agent. Anti-MRSA agent 7 inhibits S. aureus DNA gyrase, E. coli DNA gyrase, S. aureus topo IV and E. coli topo IV with IC50s of 0.185, 0.365, 0.341 and 0.059 μM, respectively[1].
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Anti-MRSA agent 7 | Anti-MRSA agent 7 (Compound 12) is a potent antibacterial agent. Anti-MRSA agent 7 inhibits S. aureus DNA gyrase, E. coli DNA gyrase, S. aureus topo IV and E. coli topo IV with IC50s of 0.185, 0.365, 0.341 and 0.059 μM, respectively. | |||||||||||||||||||||
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References
Keywords
