3053885-69-8
3053885-69-8
Chemical Structure
Aurora kinase-IN-10
- CAS No.: 3053885-69-8
- Formula:C26H26FN7O
- Molecular Weight:471.53
InChIKey: LEMRSMMWXAIQMU-BJMVGYQFSA-N
SMILES: CC(N1CCN(CC1)C2=CC=C3C(N=C(N=C3NC4=NNC(C)=C4)/C=C/C5=CC=C(C=C5)F)=C2)=O
Biological Activity: Aurora kinase-IN-10 is an Aurora kinase inhibitor. Aurora kinase-IN-10 exhibits IC50 values of 5.94 nM and 86.06 nM against Aurora A and Aurora B, respectively. Aurora kinase-IN-10 has anti-tumor activity and can be used in the research of tumors such as triple-negative breast cancer[1].
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Aurora kinase-IN-10 | Aurora kinase-IN-10 is an Aurora kinase inhibitor. Aurora kinase-IN-10 exhibits IC50 values of 5.94 nM and 86.06 nM against Aurora A and Aurora B, respectively. Aurora kinase-IN-10 has anti-tumor activity and can be used in the research of tumors such as triple-negative breast cancer. | |||||||||||||||||||||
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References
Keywords
