3057053-16-1
3057053-16-1
Chemical Structure
JAK2-IN-23
- CAS No.: 3057053-16-1
- Formula:C25H27N7O4
- Molecular Weight:489.53
InChIKey: JOJGBADFIPBXGY-IAGOWNOFSA-N
SMILES: O=C1N([C@H]2C[C@@H](CC2)NC(OC)=O)C3=CC(NC4=CC=CC(C5=CN=C(OC)C=C5)=N4)=NC=C3N1C
Biological Activity: JAK2-IN-23 is a highly selective JH2-binding JAK2 inhibitor, with an IC50 ≤ 10 nM for binding to both wild-type and V617F-mutated JH2. JAK2-IN-23 can be used in studies of JAK2-related diseases, such as cancer[1].
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JAK2-IN-23 | JAK2-IN-23 is a highly selective JH2-binding JAK2 inhibitor, with an IC50 ≤ 10 nM for binding to both wild-type and V617F-mutated JH2. JAK2-IN-23 can be used in studies of JAK2-related diseases, such as cancer. | |||||||||||||||||||||
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References
Keywords
