3058317-61-3
3058317-61-3
Chemical Structure
WRN inhibitor 11
- CAS No.: 3058317-61-3
- Formula:C34H35ClF3N9O5
- Molecular Weight:742.15
InChIKey: AEQQRWBPGUGJSK-UHFFFAOYSA-N
SMILES: CCC1=C(C(N2N=C(N=C2N1CC(NC3=CC(Cl)=C(C=C3C)C(F)(F)F)=O)C4=CCOCC4)=O)N5C6CN(C(C7=NC=NC(C)=C7O)=O)CC5CC6
Biological Activity: WRN inhibitor 11 (Example 17) is an orally active inhibitor of WRN helicase, with the IC50 of 63 nM[1].
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WRN inhibitor 11 | WRN inhibitor 11 (Example 17) is an orally active inhibitor of WRN helicase, with the IC50 of 63 nM. | |||||||||||||||||||||
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References
Keywords
