3070514-51-8
Chemical Structure
NFE2L1 activator-1
- CAS No.: 3070514-51-8
- Formula:C26H31NO7S
- Molecular Weight:501.59
InChIKey: HUNVGVZBGQQUPN-AYKLPDECSA-N
SMILES: COC1=C(OC)C=CC(/C=C2CC(NS(=O)(CC)=O)C/C(C\2=O)=C\C3=CC=C(OC)C(OC)=C3)=C1
Biological Activity: NFE2L1 activator-1 (Compound 5b) is a potent nuclear factor erythroid 2-related factor 1 (NFE2L1) activator (EC50 = 2.4 µM). NFE2L1 activator-1 effectively resists ferroptosis (Ferroptosis). NFE2L1 activator-1 can specifically activate the NFE2L1 signaling pathway to upregulate GPX4, PSMB7, PSMC4. NFE2L1 activator-1 can be used in cancer research[1].
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NFE2L1 activator-1 | 98.93% | NFE2L1 activator-1 (Compound 5b) is a potent nuclear factor erythroid 2-related factor 1 (NFE2L1) activator (EC50 = 2.4 µM). NFE2L1 activator-1 effectively resists ferroptosis (Ferroptosis). NFE2L1 activator-1 can specifically activate the NFE2L1 signaling pathway to upregulate GPX4, PSMB7, PSMC4. NFE2L1 activator-1 can be used in cancer research. | ||||||||||||||||||||
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Keywords