3074990-47-6
3074990-47-6
Chemical Structure
TEAD-IN-23
- CAS No.: 3074990-47-6
- Formula:C23H18ClF3N2O2
- Molecular Weight:446.85
InChIKey: ZSCUPUNDYXWNOA-UHFFFAOYSA-N
SMILES: CC1=CC(C2=CN(C3=C2C(Cl)=NC=C3)CCO)=CC(OC4=CC=C(C=C4)C(F)(F)F)=C1
Biological Activity: TEAD-IN-23 (Compound 22) is an efficient pan-TEAD inhibitor with an IC50 of 10 nM. TEAD-IN-23 exhibits potent anti-proliferative activity in both NCI-H226 and MSTO-211H. TEAD-IN-23 causes complete tumor regression in the MSTO-211H xenograft tumor model. TEAD-IN-23 can be used for the study of mesothelioma and hepatocellular carcinoma[1].
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TEAD-IN-23 | TEAD-IN-23 (Compound 22) is an efficient pan-TEAD inhibitor with an IC50 of 10 nM. TEAD-IN-23 exhibits potent anti-proliferative activity in both NCI-H226 and MSTO-211H. TEAD-IN-23 causes complete tumor regression in the MSTO-211H xenograft tumor model. TEAD-IN-23 can be used for the study of mesothelioma and hepatocellular carcinoma. | |||||||||||||||||||||
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References
Keywords
