3081926-49-7
Chemical Structure
DNJ-20
- CAS No.: 3081926-49-7
- Formula:C31H41NO10
- Molecular Weight:587.66
SMILES: O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=C1C(OCCCCCCCCCCN4[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C4)=CC(O)=C3
Biological Activity: DNJ-20 is an α-glucosidase inhibitor (IC50: 55.3 μg/mL). DNJ-20 has broad-spectrum anti-SARS-CoV-2 activity. DNJ-20 inhibits the correct processing of viral glycoproteins by interfering with the endoplasmic reticulum-associated glycoprotein folding process (ERQC), thereby blocking the formation and infection of viral particles. DNJ-20 has IC50 values up to 1.49 uM against several SARS-CoV-2 variants, as well as HCoV-229E and HCoV-0C43。DNJ-20 can be used for pan-coronavirus research[1].
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DNJ-20 | DNJ-20 is an α-glucosidase inhibitor (IC50: 55.3 μg/mL). DNJ-20 has broad-spectrum anti-SARS-CoV-2 activity. DNJ-20 inhibits the correct processing of viral glycoproteins by interfering with the endoplasmic reticulum-associated glycoprotein folding process (ERQC), thereby blocking the formation and infection of viral particles. DNJ-20 has IC50 values up to 1.49 uM against several SARS-CoV-2 variants, as well as HCoV-229E and HCoV-0C43。DNJ-20 can be used for pan-coronavirus research. | |||||||||||||||||||||
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Keywords
