3085413-64-2
Chemical Structure
α-Amylase-IN-13
- CAS No.: 3085413-64-2
- Formula:C17H13F3N4O2S2
- Molecular Weight:426.44
InChIKey: KUEFMFPLFRCMTP-WQLSENKSSA-N
SMILES: O=C(NC1=CC=C(C(F)(F)F)C=C1)CN(C/2=O)C(SC2=C/C3=NC=CN3C)=S
Biological Activity: α-Amylase-IN-13 is an orally active, selective, brain-penetrant α-amylase inhibitor (IC50 = 0.71 μM). α-Amylase-IN-13 inhibits α-amylase through a mixed type of inhibition mechanism. α-Amylase-IN-13 leads to a significant reduction in blood glucose level in diabetic rats. α-Amylase-IN-13 causes significant histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 can be used for the study of diabetic complications[1].
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α-Amylase-IN-13 | α-Amylase-IN-13 is an orally active, selective, brain-penetrant α-amylase inhibitor (IC50 = 0.71 μM). α-Amylase-IN-13 inhibits α-amylase through a mixed type of inhibition mechanism. α-Amylase-IN-13 leads to a significant reduction in blood glucose level in diabetic rats. α-Amylase-IN-13 causes significant histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 can be used for the study of diabetic complications. | |||||||||||||||||||||
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Keywords
