3092408-38-0
Chemical Structure
AMG 1541
- CAS No.: 3092408-38-0
- Formula:C102H186N6O18
- Molecular Weight:1784.63
IUPAC Name: (1,4,7,10,13,16-hexaazacyclooctadecane-1,4,7,10,13,16-hexayl)hexakis(2-hydroxypropane-3,1-diyl) (5Z,5'Z,5''Z,5'''Z,5''''Z,5'''''Z)-hexakis(dodec-5-enoate)
InChIKey: VVNZJBZUSOWDSM-OHHWYPJWSA-N
SMILES: C(C(COC(CCC/C=C\CCCCCC)=O)O)N1CCN(CC(COC(CCC/C=C\CCCCCC)=O)O)CCN(CC(COC(CCC/C=C\CCCCCC)=O)O)CCN(CC(COC(CCC/C=C\CCCCCC)=O)O)CCN(CC(COC(CCC/C=C\CCCCCC)=O)O)CCN(CC(COC(CCC/C=C\CCCCCC)=O)O)CC1
Biological Activity: AMG 1541 is a degradable ionizable lipid. AMG 1541 mediates the delivery of polynucleotides including mRNA. AMG 1541 exerts potent neutralizing effects on pseudotyped lentiviruses carrying the B.1.617.2 spike protein. As a component of influenza vaccines, AMG 1541 enables robust immune activation and reduces vaccine dosage. AMG 1541 is applicable to research related to SARS-CoV-2 infection[1].
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AMG 1541 | AMG 1541 is a degradable ionizable lipid. AMG 1541 mediates the delivery of polynucleotides including mRNA. AMG 1541 exerts potent neutralizing effects on pseudotyped lentiviruses carrying the B.1.617.2 spike protein. As a component of influenza vaccines, AMG 1541 enables robust immune activation and reduces vaccine dosage. AMG 1541 is applicable to research related to SARS-CoV-2 infection. | |||||||||||||||||||||
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Keywords
