3103336-29-1
3103336-29-1
Chemical Structure
MASP-2-IN-1
- CAS No.: 3103336-29-1
- Formula:C22H21N7O3S
- Molecular Weight:463.51
InChIKey: GXRJVYGQDVQTHK-UHFFFAOYSA-N
SMILES: NC1=NC(C2=CC=C(C=C2)CNC(CC3=NC=C(C=N3)NS(=O)(C4=CC=CC=C4)=O)=O)=CN1
Biological Activity: MASP-2-IN-1 (Compound 77) is a selective MASP-2 inhibitor with an IC50 of 0.0114 μM, and an IC50 of 13.2 μM against MASP-3. MASP-2-IN-1 inhibits the catalytic activity of MASP-2 in the lectin complement pathway. MASP-2-IN-1 is applicable to the research of immune diseases[1].
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MASP-2-IN-1 | MASP-2-IN-1 (Compound 77) is a selective MASP-2 inhibitor with an IC50 of 0.0114 μM, and an IC50 of 13.2 μM against MASP-3. MASP-2-IN-1 inhibits the catalytic activity of MASP-2 in the lectin complement pathway. MASP-2-IN-1 is applicable to the research of immune diseases. | |||||||||||||||||||||
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References
Keywords
