3104566-26-6
3104566-26-6
Chemical Structure
FAK-IN-29
- CAS No.: 3104566-26-6
- Formula:C26H27FN8O2
- Molecular Weight:502.54
InChIKey: WZFXJBKBYMRVRG-UHFFFAOYSA-N
SMILES: O=C(NC)C1=CC=CC=C1NC2=C3C(NC=C3F)=NC(NC4=CC=CC(CC(N5CCNCC5)=O)=C4)=N2
Biological Activity: FAK-IN-29 is a selective FAK inhibitor with an IC50 of 0.5 nM. FAK-IN-29 can inhibit the proliferation and colony formation of MDA-MB-231 cells, and induce cell cycle arrest and apoptosis. FAK-IN-29 exhibits antitumor activity and can be used for the research of tumors such as triple-negative breast cancer[1].
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FAK-IN-29 | FAK-IN-29 is a selective FAK inhibitor with an IC50 of 0.5 nM. FAK-IN-29 can inhibit the proliferation and colony formation of MDA-MB-231 cells, and induce cell cycle arrest and apoptosis. FAK-IN-29 exhibits antitumor activity and can be used for the research of tumors such as triple-negative breast cancer. | |||||||||||||||||||||
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References
Keywords
