3116847-13-0
Chemical Structure
MrgprX2 antagonist-11
- CAS No.: 3116847-13-0
- Formula:C26H28FN5O4
- Molecular Weight:493.53
InChIKey: XEGCOIVGCYWWFQ-KRWDZBQOSA-N
SMILES: O=C(C(C=C1)=CNC1=O)N2C(C)(CN(CC2)[C@@H](C)C(NC3=CC=C(C=N3)OC4=CC=C(C=C4)F)=O)C
Biological Activity: MrgprX2 antagonist-11 is a potent MrgprX2 antagonist. MrgprX2 antagonist-11 inhibits MrgprX2-mediated accumulation and mast cell degranulation (IC50 < 100 nM), thereby blocking mast cell activation. MrgprX2 antagonist-11 can be used in research on MrgprX2-related inflammatory and allergic diseases[1].
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MrgprX2 antagonist-11 | 99.32% | MrgprX2 antagonist-11 is a potent MrgprX2 antagonist. MrgprX2 antagonist-11 inhibits MrgprX2-mediated accumulation and mast cell degranulation (IC50 < 100 nM), thereby blocking mast cell activation. MrgprX2 antagonist-11 can be used in research on MrgprX2-related inflammatory and allergic diseases. | ||||||||||||||||||||
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Keywords