3120155-78-1

EGFR/BRAFV600E-IN-6 Chemical Structure
3120155-78-1

Chemical Structure

EGFR/BRAFV600E-IN-6

  • CAS No.: 3120155-78-1
  • Formula:C28H21N5O3S
  • Molecular Weight:507.56

InChIKey: SYIZCKCODVXFJJ-UHFFFAOYSA-N

SMILES: COC(C=C1)=CC=C1C2=C(C#N)C(NC(C(C=C3)=CC=C3NC(CSC4=NC5=CC=CC=C5N4)=O)=C2)=O

Biological Activity: EGFR/BRAFV600E-IN-6 (Compound 7c) is a dual EGFR/BRAFV600E inhibitor with IC50 values of 0.12 and 0.05 μM. EGFR/BRAFV600E-IN-6 can activate caspase-3/8/9, unregulate Bax expression and downregulate Bcl-2 levels. EGFR/BRAFV600E-IN-6 can induce apoptosis and shows antioxidant activity. EGFR/BRAFV600E-IN-6 can be used for the research of cancer, such as colon cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-180154 		EGFR/BRAFV600E-IN-6 EGFR/BRAFV600E-IN-6 (Compound 7c) is a dual EGFR/BRAFV600E inhibitor with IC50 values of 0.12 and 0.05 μM. EGFR/BRAFV600E-IN-6 can activate caspase-3/8/9, unregulate Bax expression and downregulate Bcl-2 levels. EGFR/BRAFV600E-IN-6 can induce apoptosis and shows antioxidant activity. EGFR/BRAFV600E-IN-6 can be used for the research of cancer, such as colon cancer.
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