3128805-51-3
Chemical Structure
L05-EXd
- CAS No.: 3128805-51-3
- Formula:C64H76FN9O25
- Molecular Weight:1390.33
InChIKey: WGLWLTPGIFUARE-RMZPKCTOSA-N
SMILES: OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(C=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=C(C=C2)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCN9C(C=CC9=O)=O)=O)=O)=O)=O)=O
Biological Activity: L05-EXd is a toxin-linker conjugate, in which the toxin component is Exatecan (HY-13631). L05-EXd can be conjugated with Polatuzumab (HY-P99042) to form the ADC molecule Polatuzumab-L05-EXd. L05-EXd is applicable to research related to small cell lung cancer and non-small cell lung cancer[1].
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L05-EXd | L05-EXd is a toxin-linker conjugate, in which the toxin component is Exatecan (HY-13631). L05-EXd can be conjugated with Polatuzumab (HY-P99042) to form the ADC molecule Polatuzumab-L05-EXd. L05-EXd is applicable to research related to small cell lung cancer and non-small cell lung cancer. | |||||||||||||||||||||
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Keywords
