327056-26-8
327056-26-8
Chemical Structure
AZD 9272
- CAS No.: 327056-26-8
- Formula:C14H6F2N4O
- Molecular Weight:284.22
IUPAC Name: 3-fluoro-5-(3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
InChIKey: RBSPCALDSNXWEP-UHFFFAOYSA-N
SMILES: N#CC1=CC(F)=CC(C2=NC(C3=CC=C(F)C=N3)=NO2)=C1
Biological Activity: AZD 9272 is a selective, orally active and brain penetrant mGluR5 antagonist with IC50s of 2.6 nM and 7.6 nM for rat and human receptors, respectively. AZD 9272 shows >3900-fold selectivity over other mGlu receptors[1]2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD 9272 | 99.87% | AZD 9272 is a selective, orally active and brain penetrant mGluR5 antagonist with IC50s of 2.6 nM and 7.6 nM for rat and human receptors, respectively. AZD 9272 shows >3900-fold selectivity over other mGlu receptors2]. | ||||||||||||||||||||
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AZD 9272 (Standard) | ≥98% | AZD 9272 (Standard) is the analytical standard of AZD 9272. This product is intended for research and analytical applications. AZD 9272 is a brain penetrant mGluR5 antagonist. | ||||||||||||||||||||
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References
Keywords
