34023-49-9
34023-49-9
Chemical Structure
H-Phe(4-SO3H)-OH
Synonym(s): 4-Sulfo-L-phenylalanine
- CAS No.: 34023-49-9
- Formula:C9H11NO5S
- Molecular Weight:245.25
IUPAC Name: (S)-2-amino-3-(4-sulfophenyl)propanoic acid
InChIKey: ALQIUGWFHKQQHV-QMMMGPOBSA-N
SMILES: S(=O)(=O)(O)C1=CC=C(C[C@@H](C(O)=O)N)C=C1
Biological Activity: H-Phe(4-SO3H)-OH (4-Sulfo-L-phenylalanine) is a L-phenylalanine (HY-N0215) derivative. H-Phe(4-SO3H)-OH induces apoptosis, chromatin margination, and inhibits cell growth in human colon cancer cells. H-Phe(4-SO3H)-OH can be used for the research of colon cancer[1][2].
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H-Phe(4-SO3H)-OH | H-Phe(4-SO3H)-OH (4-Sulfo-L-phenylalanine) is a L-phenylalanine (HY-N0215) derivative. H-Phe(4-SO3H)-OH induces apoptosis, chromatin margination, and inhibits cell growth in human colon cancer cells. H-Phe(4-SO3H)-OH can be used for the research of colon cancer. | |||||||||||||||||||||
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References
- [1]. Etoga JL, et al. Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter. Bioorg Med Chem Lett. 2010;20(8):2680-2683. [Content Brief]
- [2]. Qianyi Zhao, et al. Synthesis of Six Phenylalanine Derivatives and their Cell Toxicity Effect on Human Colon Cancer Cell Line HT-29. Letters in Drug Design & Discovery, Volume 12, Issue 6, Jul 2015, p. 466-470.
Keywords
