country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-W550859

Copy Link Print Information

H-Phe(4-SO3H)-OH

(Synonyms: 4-Sulfo-L-phenylalanine)

H-Phe(4-SO₃H)-OH (4-Sulfo-L-phenylalanine) is a L-phenylalanine (HY-N0215) derivative. H-Phe(4-SO₃H)-OH induces apoptosis, chromatin margination, and inhibits cell growth in human colon cancer cells. H-Phe(4-SO₃H)-OH can be used for the research of colon cancer.

For research use only. We do not sell to patients.

CAS No.: 34023-49-9
Formula: C₉H₁₁NO₅S
Molecular Weight:245.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

H-Phe(4-SO3H)-OH Chemical Structure

CAS No.: 34023-49-9

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

H-Phe(4-SO₃H)-OH (24-120 h) exhibits cytotoxicity against human colon cancer cell line HT-29 with an LD₅₀ of 8.2 mmol at 120 h^[2].
H-Phe(4-SO₃H)-OH (24-120 h) induces apoptosis in human colon cancer cell line HT-29, evidenced by chromatin marginalization, apoptotic body formation, and reduced cell numbers over 24 h to 120 h of treatment^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 34023-49-9
Molecular Weight 245.25
Formula C₉H₁₁NO₅S
SMILES

S(=O)(=O)(O)C1=CC=C(C[C@@H](C(O)=O)N)C=C1
Synonyms

4-Sulfo-L-phenylalanine
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Etoga JL, et al. Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter. Bioorg Med Chem Lett. 2010;20(8):2680-2683. [Content Brief]

[2]. Qianyi Zhao, et al. Synthesis of Six Phenylalanine Derivatives and their Cell Toxicity Effect on Human Colon Cancer Cell Line HT-29. Letters in Drug Design & Discovery, Volume 12, Issue 6, Jul 2015, p. 466-470.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote