353781-42-7
Chemical Structure
BRD2577
- CAS 番号: 353781-42-7
- Formula:C15H15N3O3S
- Molecular Weight:317.36
IUPAC Name: N-(4-(2-((6-methyl-4-oxo-1,4-dihydropyrimidin-2-yl)thio)acetyl)phenyl)acetamide
InChIKey: NZVOKXQPGIDGBV-UHFFFAOYSA-N
SMILES: O=C1N=C(SCC(=O)C2=CC=C(C=C2)NC(=O)C)NC(=C1)C
Biological Activity: BRD2577 is a selective mercaptopyruvate sulfurtransferase (3-MST) inhibitor with an IC50 of 9.9 μM. BRD2577 inhibits H2S production in colon carcinoma cells. BRD2577 exhibits weak to no significant inhibitory effect on colon cancer cell proliferation and mitochondrial activity. BRD2577 can be used for the research of colon cancer[1].
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BRD2577 | BRD2577 is a selective mercaptopyruvate sulfurtransferase (3-MST) inhibitor with an IC50 of 9.9 μM. BRD2577 inhibits H2S production in colon carcinoma cells. BRD2577 exhibits weak to no significant inhibitory effect on colon cancer cell proliferation and mitochondrial activity. BRD2577 can be used for the research of colon cancer. | |||||||||||||||||||||
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Keywords
