354155-51-4
354155-51-4
Chemical Structure
Endochin
- CAS No.: 354155-51-4
- Formula:C18H25NO2
- Molecular Weight:287.40
IUPAC Name: 3-heptyl-7-methoxy-2-methylquinolin-4(1H)-one
InChIKey: BCZRFDKLLBFOHJ-UHFFFAOYSA-N
SMILES: O=C1C(CCCCCCC)=C(C)NC2=C1C=CC(OC)=C2
Biological Activity: Endochin is an antimalarial agent. Endochin inhibits T.gondii with an IC50 of 0.003 nM. Endochin is also active against experimental toxoplasmosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Endochin | 99.41% | Endochin is an antimalarial agent. Endochin inhibits T.gondii with an IC50 of 0.003 nM. Endochin is also active against experimental toxoplasmosis. | ||||||||||||||||||||
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References
- [1]. Doggett JS, et al. Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15936-41. [Content Brief]
- [2]. Cross RM, et al. Endochin optimization: structure-activity and structure-property relationship studies of 3-substituted 2-methyl-4(1H)-quinolones with antimalarial activity. J Med Chem. 2010 Oct 14;53(19):7076-94. [Content Brief]
Keywords
