383150-41-2
383150-41-2
Chemical Structure
JTE-013
- CAS No.: 383150-41-2
- Formula:C17H19Cl2N7O
- Molecular Weight:408.29
IUPAC Name: N-(2,6-dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazine-1-carboxamide
InChIKey: RNSLRQNDXRSASX-UHFFFAOYSA-N
SMILES: CC(C1=C2C(N(C)N=C2C)=NC(NNC(NC3=CC(Cl)=NC(Cl)=C3)=O)=C1)C
Biological Activity: JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JTE-013 | 99.57% | JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively. | ||||||||||||||||||||
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JTE-013 (Standard) | ≥98% | JTE-013 (Standard) is the analytical standard of JTE-013. This product is intended for research and analytical applications. JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively. | ||||||||||||||||||||
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References
Keywords
