410545-90-3
Chemical Structure
L-870812
- CAS No.: 410545-90-3
- Formula:C21H20FN5O4
- Molecular Weight:425.41
IUPAC Name: N1-(7-((4-fluorobenzyl)carbamoyl)-8-hydroxy-1,6-naphthyridin-5-yl)-N1,N2,N2-trimethyloxalamide
InChIKey: DKMXWAOCNKDQMT-UHFFFAOYSA-N
SMILES: O=C(N(C1=C2C=CC=NC2=C(O)C(C(NCC3=CC=C(F)C=C3)=O)=N1)C)C(N(C)C)=O
Biological Activity: L-870812 is a HIV-1 integration with integrase strand transfer inhibitor. L-870812 consistently blocks cell-free and cell-associated HIV-1 infection. L-870812 blocks subtype C and CRFO2_AG primary isolates. L-870812 can be used for the study of replication-deficient HIV-1 Ba-L (env) pseudovirus[1].
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L-870812 | L-870812 is a HIV-1 integration with integrase strand transfer inhibitor. L-870812 consistently blocks cell-free and cell-associated HIV-1 infection. L-870812 blocks subtype C and CRFO2_AG primary isolates. L-870812 can be used for the study of replication-deficient HIV-1 Ba-L (env) pseudovirus. | |||||||||||||||||||||
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Keywords