427899-21-6
Chemical Structure
NE21650
- CAS No.: 427899-21-6
- Formula:C8H13NO7P2
- Molecular Weight:297.14
IUPAC Name: (2-(2-aminophenyl)-1-hydroxyethane-1,1-diyl)bis(phosphonic acid)
InChIKey: VJXYJONFUZXZJZ-UHFFFAOYSA-N
SMILES: OC(P(O)(O)=O)(P(O)(O)=O)CC1=CC=CC=C1N
Biological Activity: NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro[1].
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NE21650 | NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro. | |||||||||||||||||||||
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Keywords