433224-09-0
433224-09-0
Chemical Structure
TIE-2/VEGFR-2 kinase-IN-3
- CAS No.: 433224-09-0
- Formula:C23H17F4N5O3S
- Molecular Weight:519.47
InChIKey: KBJVFZCXZGSCFO-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=C(N1)C=C(SC3=CC=C(NC(NC4=CC(C(F)(F)F)=CC=C4F)=O)C=C3)C=C2)OC
Biological Activity: TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 6.9 nM and 3.5 nM, respectively. TIE-2/VEGFR-2 kinase-IN-3 can be used for the research of angiogenesis[1].
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TIE-2/VEGFR-2 kinase-IN-3 | TIE-2/VEGFR-2 kinase-IN-3, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 6.9 nM and 3.5 nM, respectively. TIE-2/VEGFR-2 kinase-IN-3 can be used for the research of angiogenesis. | |||||||||||||||||||||
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References
Keywords
