433224-29-4
Chemical Structure
TIE-2/VEGFR-2 kinase-IN-4
- CAS No.: 433224-29-4
- Formula:C26H17F4N5O4
- Molecular Weight:539.44
InChIKey: ODKIFGJQIHHLAP-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C=C2)OC3=CC4=C(N=C(N4)NC(C5=CC=CO5)=O)C=C3
Biological Activity: TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 5.2 nM and 5.1 nM, respectively. TIE-2/VEGFR-2 kinase-IN-4 can be used for the research of angiogenesis[1].
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TIE-2/VEGFR-2 kinase-IN-4 | TIE-2/VEGFR-2 kinase-IN-4, benzimidazole, is a potent TIE-2 and VEGFR-2 tyrosine kinase receptors inhibitors with IC50 values of 5.2 nM and 5.1 nM, respectively. TIE-2/VEGFR-2 kinase-IN-4 can be used for the research of angiogenesis. | |||||||||||||||||||||
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Keywords