49720-72-1
Chemical Structure
N-Deacetylcolchicine tartrate
- CAS No.: 49720-72-1
- Formula:C24H29NO11
- Molecular Weight:507.49
IUPAC Name: (S)-7-amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one (2R,3R)-2,3-dihydroxysuccinate
InChIKey: JLRWNBXMQCGSEJ-APBURCQWSA-N
SMILES: OC([C@H](O)[C@@H](O)C(O)=O)=O.O=C1C=C2[C@@H](N)CCC3=CC(OC)=C(OC)C(OC)=C3C2=CC=C1OC
Biological Activity: N-Deacetylcolchicine tartrate is a microtubule polymerization inhibitor with an IC50 of 3 μM against bovine brain microtubules. N-Deacetylcolchicine tartrate is a derivative of Colchicine (HY-16569). N-Deacetylcolchicine tartrate can activate the GTPase activity of microtubules and can be used for the research of cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
N-Deacetylcolchicine tartrate | N-Deacetylcolchicine tartrate is a microtubule polymerization inhibitor with an IC50 of 3 μM against bovine brain microtubules. N-Deacetylcolchicine tartrate is a derivative of Colchicine (HY-16569). N-Deacetylcolchicine tartrate can activate the GTPase activity of microtubules and can be used for the research of cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Muzaffar, A., et al. Antitubulin effects of derivatives of 3-demethylthiocolchicine, methylthio ethers of natural colchicinoids, and thioketones derived from thiocolchicine. Comparison with colchicinoids. J. Med. Chem. 33(2), 567-571 (1990). [Content Brief]
- [2]. Lin, et al. Effects of inhibitors of tubulin polymerization on GTP hydrolysis. The Journal of Biological Chemisty 256(17), 9242-9245 (1981). [Content Brief]
Keywords
