53177-12-1
53177-12-1
Chemical Structure
Manganese(salen) chloride
Synonym(s): EUK-8
- CAS No.: 53177-12-1
- Formula:C16H14ClMnN2O2
- Molecular Weight:356.69
InChIKey: HBQGFROGWOHBAG-SNTCFBDDSA-K
SMILES: [Cl-][Mn+3]123[O-]C4=C(C=[N]1CC[N]2=CC5=C([O-]3)C=CC=C5)C=CC=C4
Biological Activity: Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine[1][2].
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Manganese(salen) chloride | 97.38% | Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine. | ||||||||||||||||||||
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References
- [1]. Gonzalez PK, et, al. EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine. J Pharmacol Exp Ther. 1995 Nov;275(2):798-806. [Content Brief]
- [2]. Bruce AJ, et, al. beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2312-6. [Content Brief]
Keywords
