543700-67-0
Chemical Structure
BMS-433771 dihydrochloride hydrate
- CAS No.: 543700-67-0
- Formula:C21H27Cl2N5O3
- Molecular Weight:468.38
IUPAC Name: 1-cyclopropyl-3-((1-(4-hydroxybutyl)-1H-benzo[d]imidazol-2-yl)methyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one dihydrochloride hydrate
InChIKey: DMSGBVAHVFUZMJ-UHFFFAOYSA-N
SMILES: O=C(N1C2CC2)N(CC3=NC4=CC=CC=C4N3CCCCO)C5=C1C=CN=C5.[H]Cl.[H]Cl.[H]O[H]
Biological Activity: BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease[1][2].
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BMS-433771 dihydrochloride hydrate | 98.00% | BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease. | ||||||||||||||||||||
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- [1]. Christopher Cianci, et al. Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor. J Antimicrob Chemother [Content Brief]
- [2]. Christopher Cianci, et al. Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection. Antimicrob Agents Chemother. 2004 Jul;48(7):2448-54. [Content Brief]
Keywords
