562823-84-1
562823-84-1
Chemical Structure
TLBC
- CAS No.: 562823-84-1
- Formula:C15H12BIO3
- Molecular Weight:377.97
IUPAC Name: (E)-(4-(3-(4-iodophenyl)acryloyl)phenyl)boronic acid
InChIKey: BYMGWCQXSPGCMW-XCVCLJGOSA-N
SMILES: OB(C1=CC=C(C(/C=C/C2=CC=C(I)C=C2)=O)C=C1)O
Biological Activity: TLBC, a boronic-chalcone derivative, shows a dose-dependent inhibition with IC50 values of 5.5-25.5 μM in various glioma cell lines. TLBC induces apoptosis independent of changes to the tumor suppressor p53[1].
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TLBC | TLBC, a boronic-chalcone derivative, shows a dose-dependent inhibition with IC50 values of 5.5-25.5 μM in various glioma cell lines. TLBC induces apoptosis independent of changes to the tumor suppressor p53. | |||||||||||||||||||||
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References
Keywords
