594842-13-4
Chemical Structure
Granotapide
Synonym(s): JTT-130
- CAS No.: 594842-13-4
- Formula:C39H37F3N2O8
- Molecular Weight:718.71
IUPAC Name: diethyl 2-((2-(3-(dimethylcarbamoyl)-4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamido)phenyl)acetoxy)methyl)-2-phenylmalonate
InChIKey: FPUQGCOBYOXAED-UHFFFAOYSA-N
SMILES: CCOC(C(C(OCC)=O)(COC(CC1=CC(C(N(C)C)=O)=C(C=C1)NC(C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)=O)=O)C4=CC=CC=C4)=O
Biological Activity: Granotapide is an orally active microsomal triglyceride transfer protein (MTP) inhibitor. Granotapide reduces the absorption of cholesterol and triglycerides by inhibiting MTP. Granotapide can be used in the research of coronary artery disease, obesity, diabetes mellitus and hypertension[1].
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Granotapide | Granotapide is an orally active microsomal triglyceride transfer protein (MTP) inhibitor. Granotapide reduces the absorption of cholesterol and triglycerides by inhibiting MTP. Granotapide can be used in the research of coronary artery disease, obesity, diabetes mellitus and hypertension. | |||||||||||||||||||||
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Keywords