639074-49-0
639074-49-0
Chemical Structure
KSP-IA
- CAS No.: 639074-49-0
- Formula:C21H22F2N2O
- Molecular Weight:356.41
IUPAC Name: (S)-2-amino-1-((S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl)-3-methylbutan-1-one
InChIKey: GNFWJCGIZJCASB-PMACEKPBSA-N
SMILES: CC(C)[C@H](N)C(N1[C@H](C2=CC=CC=C2)C=C(C3=CC(F)=CC=C3F)C1)=O
Biological Activity: KSP-IA (compound 17) is a potent kinesin spindle protein (KSP) inhibitor with an IC50 value of 3.6 nM. KSP-IA inhibits cell mitosis[1].
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KSP-IA | KSP-IA (compound 17) is a potent kinesin spindle protein (KSP) inhibitor with an IC50 value of 3.6 nM. KSP-IA inhibits cell mitosis. | |||||||||||||||||||||
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References
Keywords
