667931-33-1
Chemical Structure
TAK-075
- CAS No.: 667931-33-1
- Formula:C36H46N4O4S
- Molecular Weight:630.84
InChIKey: NDWLAPXXXCPRNP-GJFSDDNBSA-N
SMILES: O=S(O)(C1=CC=C(C=C1)C)=O.CCC(CC)(C2=CC=C(C=C2)CC)NC(C3=C4N(N=C3C)C(C)(C[C@H](C5=CC=CC=C5)N4)C)=O
Biological Activity: TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. TAK-075 can stimulate the transient secretion of parathyroid hormone (PTH) in rats and can effectively prevent a significant reduction in PTH secretion caused by the accumulation of active metabolites, maintaining the normal secretion pattern of PTH. TAK-075 can be used in the research of metabolic diseases and osteoporosis[1].
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TAK-075 | TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. TAK-075 can stimulate the transient secretion of parathyroid hormone (PTH) in rats and can effectively prevent a significant reduction in PTH secretion caused by the accumulation of active metabolites, maintaining the normal secretion pattern of PTH. TAK-075 can be used in the research of metabolic diseases and osteoporosis. | |||||||||||||||||||||
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Keywords
