6742-12-7
6742-12-7
Chemical Structure
Formycin A
Synonym(s): NSC 102811
- CAS No.: 6742-12-7
- Formula:C10H13N5O4
- Molecular Weight:267.24
IUPAC Name: (2S,3R,4S,5R)-2-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChIKey: KBHMEHLJSZMEMI-KSYZLYKTSA-N
SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)C2=NNC3=C2N=CN=C3N
Biological Activity: Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Formycin A | 99.0% | Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities. | ||||||||||||||||||||
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References
- [1]. Dapp MJ , et al. Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1.J Virol. 2014 Jan;88(1):354-63. [Content Brief]
- [2]. Zhang M, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds. Appl Environ Microbiol. 2020 Jan 7;86(2). [Content Brief]
Keywords
