729589-58-6
Chemical Structure
2-Furoyl-LIGRLO-amide
- CAS No.: 729589-58-6
- Formula:C36H63N11O8
- Molecular Weight:777.95
IUPAC Name: N-((4S,7S,10S,16S,19S)-1-amino-16-((S)-sec-butyl)-4-carbamoyl-10-(3-guanidinopropyl)-7-isobutyl-21-methyl-6,9,12,15,18-pentaoxo-5,8,11,14,17-pentaazadocosan-19-yl)furan-2-carboxamide
InChIKey: OSKIRYSKGDEIOG-WTWMNNMUSA-N
SMILES: NCCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC(C1=CC=CO1)=O)=O)=O)=O)=O)=O
Biological Activity: 2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0[1][2]..
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Furoyl-LIGRLO-amide | 99.59% | 2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0.. | ||||||||||||||||||||
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- [1]. McGuire JJ, et al. 2-furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J Pharmacol Exp Ther. 2004 Jun;309(3):1124-31. [Content Brief]
- [2]. Lohman RJ, et al. An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. FASEB J. 2012 Jul;26(7):2877-87. [Content Brief]
Keywords
