72984-36-2
Chemical Structure
Chlorin e6 trisodium
Synonym(s): Ce6 trisodium
- CAS No.: 72984-36-2
- Formula:C34H33N4Na3O6
- Molecular Weight:662.62
InChIKey: GVBNHHULZRENLV-BTFXJMARSA-K
SMILES: O=C(O[Na])C/C1=C2[C@H]([C@@H](C(/C=C3N/C(C(C=C)=C\3C)=C\C4=N/C(C(CC)=C4C)=C\C5=C(C)C(C(O[Na])=O)=C1N5)=N\2)C)CCC(O[Na])=O
Biological Activity: Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3].
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Chlorin e6 trisodium | 98.92% | Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions. | ||||||||||||||||||||
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- [1]. Chin WW, et al. The potential application of chlorin e6-polyvinylpyrrolidone formulation in photodynamic therapy. Photochem Photobiol Sci. 2006 Nov;5(11):1031-7. [Content Brief]
- [2]. Chin WW, et al. Fluorescence imaging and phototoxicity effects of new formulation of chlorin e6-polyvinylpyrrolidone. J Photochem Photobiol B. 2006 Aug 1;84(2):103-10. [Content Brief]
- [3]. Rybkin AY, et al. Nanoparticles of N-Vinylpyrrolidone Amphiphilic Copolymers and Pheophorbide a as Promising Photosensitizers for Photodynamic Therapy: Design, Properties and In Vitro Phototoxic Activity. Pharmaceutics. 2023 Jan 12;15(1):273. [Content Brief]
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