73573-17-8
Chemical Structure
Puupehenone
- CAS No.: 73573-17-8
- Formula:C21H28O3
- Molecular Weight:328.45
IUPAC Name: (4aS,6aS,12aR,12bS)-10-hydroxy-4,4,6a,12b-tetramethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-9H-benzo[a]xanthen-9-one
InChIKey: LOCMLXSTDCXZFJ-YHELAOLJSA-N
SMILES: C[C@@]12[C@@]3([C@@](C)(OC=4C(=C3)C=C(O)C(=O)C4)CC[C@]1(C(C)(C)CCC2)[H])[H]
Biological Activity: Puupehenone is a cytotoxic and antifungal agent present in various marine sponge species. Puupehenone exerts cytotoxic activity against leukemia, lung cancer, colon cancer and breast cancer cells, and inhibits the growth of Candida albicans. Puupehenone can be used in research related to cancers such as leukemia, lung cancer, colon cancer and breast cancer[1][2][3].
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Puupehenone | Puupehenone is a cytotoxic and antifungal agent present in various marine sponge species. Puupehenone exerts cytotoxic activity against leukemia, lung cancer, colon cancer and breast cancer cells, and inhibits the growth of Candida albicans. Puupehenone can be used in research related to cancers such as leukemia, lung cancer, colon cancer and breast cancer. | |||||||||||||||||||||
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- [1]. Nasu SS, et al. Puupehenone-related metabolites from two Hawaiian sponges, Hyrtios spp. J Org Chem. 1995 Nov 1;60(22):7290-7292.
- [2]. Kohmoto S, et al. Puupehenone, A Cytotoxic Metabolite from a Deep Water Marine Sponge, Stronglyophora hartmani. J Nat Prod. 1987 Mar 1;50(2):336.
- [3]. Castro ME, et al. Study of puupehenone and related compounds as inhibitors of angiogenesis. Int J Cancer. 2004;110(1):31-38. [Content Brief]
Keywords