75144-12-6

Antitrypanosomal agent 1 Chemical Structure
75144-12-6

Chemical Structure

Antitrypanosomal agent 1

  • CAS No.: 75144-12-6
  • Formula:C11H14Cl3NO
  • Molecular Weight:282.59

IUPAC Name: 1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride

InChIKey: PRRKQCKNKRZOPV-UHFFFAOYSA-N

SMILES: O=C(C1=CC=C(Cl)C(Cl)=C1)CCN(C)C.[H]Cl

Biological Activity: Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity[1].

Cat. No. Product Name Purity Description Pricing
HY-W052512 		Antitrypanosomal agent 1 99.50% Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity.
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