864668-87-1
Chemical Structure
ENMD-1198
Synonym(s): IRC-110160
- CAS No.: 864668-87-1
- Formula:C20H25NO2
- Molecular Weight:311.42
IUPAC Name: (8S,9S,13R,14S)-2-methoxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthrene-3-carboxamide
InChIKey: YQJWOUQGXATDAE-ACNBBOPNSA-N
SMILES: C[C@@]12C=CC[C@@]1([H])[C@]3([H])CCC4=C(C=C(OC)C(C(N)=O)=C4)[C@@]3([H])CC2
Biological Activity: ENMD-1198 (IRC-110160), an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD-1198 is suitable for inhibiting HIF-1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization.
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ENMD-1198 | 98.48% | ENMD-1198 (IRC-110160), an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD-1198 is suitable for inhibiting HIF-1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization. | ||||||||||||||||||||
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Keywords
