868691-50-3
Chemical Structure
JNJ-26146900
- CAS No.: 868691-50-3
- Formula:C15H15F3N2O3S
- Molecular Weight:360.35
IUPAC Name: (R)-2-(1-(ethylsulfonyl)-2-hydroxypropan-2-yl)-6-(trifluoromethyl)-1H-indole-5-carbonitrile
InChIKey: UJGGNFGSHPHGNE-AWEZNQCLSA-N
SMILES: N#CC1=CC2=C(C=C1C(F)(F)F)NC([C@@](O)(CS(=O)(CC)=O)C)=C2
Biological Activity: JNJ-26146900 is a potent and orally active androgen receptor antagonist with a Ki value of 400nM for rat AR. JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand. JNJ-26146900 reduces prostate tumor size and prevents bone loss. JNJ-26146900 can be used in research of cancer[1].
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JNJ-26146900 | JNJ-26146900 is a potent and orally active androgen receptor antagonist with a Ki value of 400nM for rat AR. JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand. JNJ-26146900 reduces prostate tumor size and prevents bone loss. JNJ-26146900 can be used in research of cancer. | |||||||||||||||||||||
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Keywords