870962-74-6
Chemical Structure
EGFR/VEGFR2-IN-4
- CAS No.: 870962-74-6
- Formula:C29H29N5O5
- Molecular Weight:527.57
IUPAC Name: (E)-N-(4-((4-(benzyloxy)-3,6-dioxocyclohexa-1,4-dien-1-yl)amino)-7-ethoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide
InChIKey: OZJNFEMRGXMBKA-DHZHZOJOSA-N
SMILES: CCOC(C(NC(/C=C/CN(C)C)=O)=C1)=CC2=C1C(NC(C(C=C3OCC4=CC=CC=C4)=O)=CC3=O)=NC=N2
Biological Activity: EGFR/VEGFR2-IN-4 (Compound 19) is the irreversible inhibitor for EGFR and VEGFR-2 with IC50 of 18.7 nM and 102.3 nM, under the presence of 1 μM ATP[1].
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EGFR/VEGFR2-IN-4 | EGFR/VEGFR2-IN-4 (Compound 19) is the irreversible inhibitor for EGFR and VEGFR-2 with IC50 of 18.7 nM and 102.3 nM, under the presence of 1 μM ATP. | |||||||||||||||||||||
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Keywords