90851-28-8
Chemical Structure
Goshonoside F5
- CAS No.: 90851-28-8
- Formula:C32H54O13
- Molecular Weight:646.76
IUPAC Name: (2R,3R,4S,5S,6R)-2-(((1S,2R,4aS,5R,8aS)-2-hydroxy-1,4a-dimethyl-5-((E)-3-methyl-5-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pent-3-en-1-yl)-6-methylenedecahydronaphthalen-1-yl)methoxy)-6-(hydroxymethyl)tetrahydro-2H
InChIKey: QIOMMMCQFIBVKA-PPQBIMEKSA-N
SMILES: O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC/C=C(C)/CC[C@@H]2C(CC[C@]3([H])[C@@](C)(CO[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)[C@H](O)CC[C@@]23C)=C
Biological Activity: Goshonoside F5 can be isolated from the unripe fruits of Rubus chingii. Goshonoside F5 has anti-inflammatory activity, and inhibits NF-κB and MAPK signaling pathway[1][2].
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Goshonoside F5 | Goshonoside F5 can be isolated from the unripe fruits of Rubus chingii. Goshonoside F5 has anti-inflammatory activity, and inhibits NF-κB and MAPK signaling pathway. | |||||||||||||||||||||
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- [1]. Sun, N., et al. A new ent-labdane diterpene saponin from the fruits of Rubus chingii . Chem Nat Compd. 49, 49-53 (2013).
- [2]. He JM, et al. Suppression of nuclear factor-kappa B and mitogen-activated protein kinase signalling pathways by goshonoside-F5 extracted from Rubi Fructus. Int Immunopharmacol. 2015 Feb;24(2):182-190. [Content Brief]
Keywords
