909400-43-7
909400-43-7
Chemical Structure
Cl-HIBO
- CAS No.: 909400-43-7
- Formula:C6H7ClN2O4
- Molecular Weight:206.58
IUPAC Name: 2-amino-3-(4-chloro-3-oxo-2,3-dihydroisoxazol-5-yl)propanoic acid
InChIKey: FDSXCQTXUSQQFH-UHFFFAOYSA-N
SMILES: O=C(O)C(N)CC(ON1)=C(Cl)C1=O
Biological Activity: Cl-HIBO is a highly subtype-selective GluR1/2 agonist (EC50=4.7 and 1.7 μM, respectively). Cl-HIBO is a potent AMPA receptor agonist (IC50=0.22 μM). Cl-HIBO has desensitizing properties[1].
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Cl-HIBO | 99.0% | Cl-HIBO is a highly subtype-selective GluR1/2 agonist (EC50=4.7 and 1.7 μM, respectively). Cl-HIBO is a potent AMPA receptor agonist (IC50=0.22 μM). Cl-HIBO has desensitizing properties. | ||||||||||||||||||||
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References
Keywords
