937273-04-6
Chemical Structure
SB1578
Synonym(s): CT-1578
- CAS No.: 937273-04-6
- Formula:C26H30N4O4
- Molecular Weight:462.54
IUPAC Name: (22E,8E)-44-(2-(pyrrolidin-1-yl)ethoxy)-21,22-dihydro-6,11-dioxa-3-aza-2(6,2)-pyrimidina-1(2,5)-furana-4(1,3)-benzenacyclododecaphan-8-ene
InChIKey: NNXDIGHYPZHXTR-ONEGZZNKSA-N
SMILES: N1(CCCC1)CCOC2=CC=C3C=C2COC/C=C/COCC4=CC=C(O4)C5=CC=N/C(N5)=N/3
Biological Activity: SB1578 (CT-1578) is a selective JAK2 and FLT3 inhibitor with an IC50 of 46 nM and 60 nM, respectively. SB1578 exhibits high selectivity for other kinase targets. SB1578 can be used for the study of non-oncology indication rheumatoid arthritis[1].
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SB1578 | SB1578 (CT-1578) is a selective JAK2 and FLT3 inhibitor with an IC50 of 46 nM and 60 nM, respectively. SB1578 exhibits high selectivity for other kinase targets. SB1578 can be used for the study of non-oncology indication rheumatoid arthritis. | |||||||||||||||||||||
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Keywords
