93801-18-4
Chemical Structure
N-(p-Aminophenethyl)spiperone
- CAS No.: 93801-18-4
- Formula:C31H35FN4O2
- Molecular Weight:514.63
IUPAC Name: 3-(4-aminophenethyl)-8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
InChIKey: OFOJSVPHSJPGKK-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1)C(CCCN2CCC3(CC2)C(N(CN3C4=CC=CC=C4)CCC5=CC=C(C=C5)N)=O)=O
Biological Activity: N-(p-Aminophenethyl) spiperone is a selective D2-like dopamine receptor antagonist. N-(p-Aminophenethyl) spiperone binds to the ligand recognition sites of functional D2 and D3 dopamine receptors. N-(p-Aminophenethyl) spiperone serves as a research tool compound for labeling, localizing and identifying D2 and D3 dopamine receptors[1][2].
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N-(p-Aminophenethyl)spiperone | N-(p-Aminophenethyl) spiperone is a selective D2-like dopamine receptor antagonist. N-(p-Aminophenethyl) spiperone binds to the ligand recognition sites of functional D2 and D3 dopamine receptors. N-(p-Aminophenethyl) spiperone serves as a research tool compound for labeling, localizing and identifying D2 and D3 dopamine receptors. | |||||||||||||||||||||
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- [1]. Larson ER, et al. D3 and D2 dopamine receptors: visualization of cellular expression patterns in motor and limbic structures. Synapse. 1995;20(4):325-337. [Content Brief]
- [2]. Amlaiky N, et al. Photoaffinity labeling of the D2-dopamine receptor using a novel high affinity radioiodinated probe. J Biol Chem. 1985;260(4):1983-1986. [Content Brief]
Keywords
